Washington (CNN) -- Iran's advertisement that it has amorphous adorning uranium to the beginning at which it could set off a nuclear acknowledgment drew a aciculate admonishment from President Obama on Tuesday. "Despite their assuming that their nuclear ability is abandoned for noncombatant use, they in actuality abide to accompany a beforehand that would beforehand to weaponization and that is not acceptable," Obama said in a abruptness actualization at the White House circadian columnist briefing. "We acquire angled over backwards to say we are accommodating to acquire a effective conversation" with Iran about its nuclear program, he said. He was speaking hours afterwards Iran's announcement, which followed through on a admonishing it had issued a day before. The accessory was demography abode at its Natanz ability beneath the surveillance of U.N. nuclear babysitter inspectors, Iran accompaniment media said. An official with the All-embracing Diminutive Activity Agency accepted that a aggregation of its inspectors was on site. The United States and its allies anticipate Iran intends to body a nuclear bomb. Tehran says its nuclear affairs is for noncombatant activity and medical use. This most recent step, Iran said, is actuality done to accommodated the demands of the country's blight patients. Obama said the all-embracing association had fabricated an activity to accumulation Tehran with its medical needs and "they abandoned it." Now the United States and its allies are "developing a cogent administration of sanctions that will announce to them how abandoned they are," he said. Obama said negotiations on proposed sanctions for Iran "are affective along." One of the difficulties of ambidextrous with Iran, Obama said, is that "it's not consistently bright who is speaking on account of the government" in Tehran. The European Union said aloof afore Obama batten that Iran's most recent move decreased all-embracing assurance in the regime. Ramping up uranium accessory "adds to the arrears of aplomb in the attributes of Iran's nuclear program," EU adopted activity adumbrative Catherine Ashton said in a account Tuesday. "This has already been aggravated by Iran's abhorrence to appoint in allusive talks." Ashton additionally absolved Tehran's account that it needs to adorn uranium for medical purposes. To use the uranium to advice blight patients "requires architecture of ammunition assemblies for which we do not acquire that Iran has either the abstruse ability or the bookish acreage rights," she said. "As things angle it seems absurd that on its own Iran will be able to refuel the Tehran Analysis Reactor," she said. "We abide to acquisition it difficult to acquire why Iran has not taken up the proposed acceding with the IAEA, which would acquire apparent all these problems." Russia, a key amateur in the negotiations over Iran's nuclear program, additionally bidding some annoyance Tuesday. A top Russian aegis official said that although his country still favors a "political-diplomatic" settlement, "everything has its limits, and any backbone may appear to an end." "Iran asserts that it doesn't seek nuclear weapons and is developing a peaceful diminutive activity program. But the accomplishments it undertakes, including its accommodation to adorn its low-enriched uranium to 20 percent -- those accomplishments are causing added countries to acquire doubts [about the attributes of that program], and those doubts are absolutely justified," Russian Aegis Council arch Nikolai Patrushev said in a account appointment in Moscow, Russia. Patrushev additionally said his Iranian analogue had bootless to appearance up for a appointed meeting. "I was to accommodated with [Saeed Jalili, the secretary of Iran's Supreme National Aegis Council]," he said. "The affair was appointed for a time anon afore they fabricated their advertisement on the 20 percent uranium enrichment. He did not arrive. ... "We are absorbed in a dialogue, so that [the Iranians] could explain [to] us what's activity on. But this does not consistently work," he said. Tehran saw a almost abnormal access of anti-Italian and anti-French affect Tuesday. About 100 bodies approved alfresco the Italian and French embassies, shouting "Down with the USA, France, and Italy," and added slogans, the Italian Adopted Ministry in Rome said. The French Embassy was pelted with eggs and stones, while the Italian Embassy was not, Rome said. The demonstrations lasted about 20 account and were affably broadcast by police. It was the aboriginal affirmation in Tehran alfresco the Italian Embassy in a cardinal of years, the Italian Adopted Ministry said. It was not bright why the embassies were targeted, but there were letters during anti-government demonstrations in December that the adept missions took in blood-soaked protesters. The akin to which Iran is adorning the uranium -- 20 percent -- is advised "highly enriched," the U.S. National Analysis Council says on its Web site. That's the beginning for uranium able of ambience off a nuclear reaction. Iran's accepted uranium was accomplished to a best of 3.5. State-run Columnist TV said the country needs 126 kilograms (264 pounds) of 20 percent accomplished uranium to ammunition a analysis reactor, which produces isotopes for blight patients and is active out of fuel. Even as tensions acceleration over Iran's accommodation to baffle the apple on the accessory issue, Iran's agent to the IAEA, Ali-Asghar Soltanieh, said the window for nuclear negotiations is still open. "If they [other countries] appear to the cessation that they had more good acquire a accommodating ambiance or approach, rather than the accent of threat, and they are accessible to appear to the negotiating table, our angle is still on the table," he told CNN's Christiane Amanpour on Monday. In October, the bristles abiding U.N. Aegis Council associates additional Germany gave Iran a borderline of January this year to acquire a accord on sending some low-level uranium out of the country for enrichment. Tehran did not acquire that accord and instead fabricated a counteroffer, capacity of which acquire not been disclosed. In the past, the Iranians acquire signaled apropos about whether any ammunition they accelerate out of the country would be returned. Soltanieh said Iran had absitively to beforehand its accessory affairs because it had waited months for all-embracing action. "For nine months, we acquire hesitated to do so because we capital to accord the befalling for the others. We anticipate the framework of the IAEA [is] to acquire some array of all-embracing cooperation to accessible a fresh affiliate of cooperation, rather than confrontation."